Fasudil inhibits proliferation and collagen synthesis and induces apoptosis of human fibroblasts derived from urethral scar via the Rho/ROCK signaling pathway

Fasudil has shown antifibrotic effects in various fibrotic diseases. However, its effects on human urethral fibroblasts are unknown. This study evaluated the effects of fasudil on cellular proliferation, migration, apoptosis, and collagen synthesis in human fibroblasts derived from urethral scar tis...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Xu, Ning, Chen, Shao-Hao, Qu, Gen-Yi, Li, Xiao-Dong, Lin, Wen, Xue, Xue-Yi, Lin, Yun-Zhi, Zheng, Qing-Shui, Wei, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376022/
https://ncbi.nlm.nih.gov/pubmed/28386357
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