Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus

Despite the recent success of newly developed direct-acting antivirals against hepatitis C, the disease continues to be a global health threat due to the lack of diagnosis of most carriers and the high cost of treatment. The heterodimer formed by glycoproteins E1 and E2 within the hepatitis C virus...

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Vydáno v:J Virol
Hlavní autoři: Freedman, Holly, Logan, Michael R., Hockman, Darren, Koehler Leman, Julia, Law, John Lok Man, Houghton, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375693/
https://ncbi.nlm.nih.gov/pubmed/28148799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02309-16
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