Targeting Vaccine-Induced Extrafollicular Pathway of B Cell Differentiation Improves Rabies Postexposure Prophylaxis

Vaccine-induced B cells differentiate along two pathways. The follicular pathway gives rise to germinal centers (GCs) that can take weeks to fully develop. The extrafollicular pathway gives rise to short-lived plasma cells (PCs) that can rapidly secrete protective antibodies within days of vaccinati...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Haley, Shannon L., Tzvetkov, Evgeni P., Meuwissen, Samantha, Plummer, Joseph R., McGettigan, James P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375675/
https://ncbi.nlm.nih.gov/pubmed/28148792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02435-16
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