Targeting Vaccine-Induced Extrafollicular Pathway of B Cell Differentiation Improves Rabies Postexposure Prophylaxis

Vaccine-induced B cells differentiate along two pathways. The follicular pathway gives rise to germinal centers (GCs) that can take weeks to fully develop. The extrafollicular pathway gives rise to short-lived plasma cells (PCs) that can rapidly secrete protective antibodies within days of vaccinati...

Full description

Saved in:
Bibliographic Details
Published in:J Virol
Main Authors: Haley, Shannon L., Tzvetkov, Evgeni P., Meuwissen, Samantha, Plummer, Joseph R., McGettigan, James P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375675/
https://ncbi.nlm.nih.gov/pubmed/28148792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02435-16
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items