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Release of Cell-free MicroRNA Tumor Biomarkers into the Blood Circulation with Pulsed Focused Ultrasound: A Noninvasive, Anatomically Localized, Molecular Liquid Biopsy

PURPOSE: To compare the abilities of three pulsed focused ultrasound regimes (that cause tissue liquefaction, permeabilization, or mild heating) to release tumor-derived microRNA into the circulation in vivo and to evaluate release dynamics. MATERIALS AND METHODS: All rat experiments were approved b...

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Detalhes bibliográficos
Publicado no:Radiology
Main Authors: Chevillet, John R., Khokhlova, Tatiana D., Giraldez, Maria D., Schade, George R., Starr, Frank, Wang, Yak-Nam, Gallichotte, Emily N., Wang, Kai, Hwang, Joo Ha, Tewari, Muneesh
Formato: Artigo
Idioma:Inglês
Publicado em: Radiological Society of North America 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375625/
https://ncbi.nlm.nih.gov/pubmed/27802108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2016160024
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