Enhancement of Small Molecule Delivery by Pulsed-High Intensity Focused Ultrasound (pHIFU): A Parameter Exploration

Chemotherapeutic drug delivery is often ineffective within solid tumors, but increasing the drug dose would result in systemic toxicity. The use of high-intensity focused ultrasound (HIFU) has the potential to enhance penetration of small molecules. However, operation parameters need to be optimized...

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Udgivet i:Ultrasound Med Biol
Main Authors: Zhou, Yufeng, Wang, Yak-Nam, Farr, Navid, Zia, Jasmine, Chen, Hong, Ko, Bong Min, Khokhlova, Tatiana, Li, Tong, Hwang, Joo Ha
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775378/
https://ncbi.nlm.nih.gov/pubmed/26803389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2015.12.009
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