A Sigmoid Functional Response Emerges When Cytotoxic T Lymphocytes Start Killing Fresh Target Cells

Cytotoxic T lymphocyte (CTL)-mediated killing involves the formation of a synapse with a target cell, followed by delivery of perforin and granzymes. Previously, we derived a general functional response for CTL killing while considering that CTLs form stable synapses (i.e., single-stage) and that th...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Gadhamsetty, Saikrishna, Marée, Athanasius F.M., Beltman, Joost B., de Boer, Rob J.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2017
Matèries:
Cell Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375173/
https://ncbi.nlm.nih.gov/pubmed/28355549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.008
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