Prediction of diuretic response to tolvaptan by a simple, readily available spot urine Na/K ratio

BACKGROUND: Tolvaptan is vasopressin type 2 receptor antagonist that inhibits water reabsorption. It is used in combination with standard diuretics to treat ascites unresponsive to standard diuretic therapy or hyponatremia because of liver cirrhosis. This study evaluated the effectiveness and safety...

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Bibliographic Details
Published in:PLoS One
Main Authors: Komiyama, Yasuyuki, Kurosaki, Masayuki, Nakanishi, Hiroyuki, Takahashi, Yuka, Itakura, Jun, Yasui, Yutaka, Tamaki, Nobuharu, Takada, Hitomi, Higuchi, Mayu, Gotou, Tomoyuki, Kubota, Youhei, Takaura, Kenta, Hayashi, Tsuguru, Oh, Wann, Okada, Mao, Enomoto, Nobuyuki, Izumi, Namiki
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375149/
https://ncbi.nlm.nih.gov/pubmed/28362879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174649
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