Prediction of diuretic response to tolvaptan by a simple, readily available spot urine Na/K ratio

BACKGROUND: Tolvaptan is vasopressin type 2 receptor antagonist that inhibits water reabsorption. It is used in combination with standard diuretics to treat ascites unresponsive to standard diuretic therapy or hyponatremia because of liver cirrhosis. This study evaluated the effectiveness and safety...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Komiyama, Yasuyuki, Kurosaki, Masayuki, Nakanishi, Hiroyuki, Takahashi, Yuka, Itakura, Jun, Yasui, Yutaka, Tamaki, Nobuharu, Takada, Hitomi, Higuchi, Mayu, Gotou, Tomoyuki, Kubota, Youhei, Takaura, Kenta, Hayashi, Tsuguru, Oh, Wann, Okada, Mao, Enomoto, Nobuyuki, Izumi, Namiki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375149/
https://ncbi.nlm.nih.gov/pubmed/28362879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174649
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