Prediction of diuretic response to tolvaptan by a simple, readily available spot urine Na/K ratio

BACKGROUND: Tolvaptan is vasopressin type 2 receptor antagonist that inhibits water reabsorption. It is used in combination with standard diuretics to treat ascites unresponsive to standard diuretic therapy or hyponatremia because of liver cirrhosis. This study evaluated the effectiveness and safety...

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Vydáno v:PLoS One
Hlavní autoři: Komiyama, Yasuyuki, Kurosaki, Masayuki, Nakanishi, Hiroyuki, Takahashi, Yuka, Itakura, Jun, Yasui, Yutaka, Tamaki, Nobuharu, Takada, Hitomi, Higuchi, Mayu, Gotou, Tomoyuki, Kubota, Youhei, Takaura, Kenta, Hayashi, Tsuguru, Oh, Wann, Okada, Mao, Enomoto, Nobuyuki, Izumi, Namiki
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375149/
https://ncbi.nlm.nih.gov/pubmed/28362879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174649
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