Prediction of diuretic response to tolvaptan by a simple, readily available spot urine Na/K ratio

BACKGROUND: Tolvaptan is vasopressin type 2 receptor antagonist that inhibits water reabsorption. It is used in combination with standard diuretics to treat ascites unresponsive to standard diuretic therapy or hyponatremia because of liver cirrhosis. This study evaluated the effectiveness and safety...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Komiyama, Yasuyuki, Kurosaki, Masayuki, Nakanishi, Hiroyuki, Takahashi, Yuka, Itakura, Jun, Yasui, Yutaka, Tamaki, Nobuharu, Takada, Hitomi, Higuchi, Mayu, Gotou, Tomoyuki, Kubota, Youhei, Takaura, Kenta, Hayashi, Tsuguru, Oh, Wann, Okada, Mao, Enomoto, Nobuyuki, Izumi, Namiki
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375149/
https://ncbi.nlm.nih.gov/pubmed/28362879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174649
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