Targeted interneuron depletion in the dorsal striatum produces autism-like behavioral abnormalities in male but not female mice

BACKGROUND: Interneuronal pathology is implicated in many neuropsychiatric disorders, including autism spectrum disorder (ASD) and Tourette syndrome (TS). Interneurons of the striatum, including the parvalbumin-expressing fast-spiking interneurons (FSIs) and the large cholinergic interneurons (CINs)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biol Psychiatry
Prif Awduron: Rapanelli, Maximiliano, Frick, Luciana Romina, Xu, Meiyu, Groman, Stephanie Mary, Jindachomthong, Kantiya, Tamamaki, Nobuaki, Tanahira, Chiyoko, Taylor, Jane Rebecca, Pittenger, Christopher
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374721/
https://ncbi.nlm.nih.gov/pubmed/28347488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.01.020
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