Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat

BACKGROUND: MyD88 is the adaptor protein of MyD88-dependent signaling pathway of TLRs and IL-1 receptor and regulates innate immune response. However, it was not clear whether and how MyD88 and related signaling pathways in the dorsal root ganglion (DRG) and spinal dorsal horn (SDH) are involved in...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Liu, Fan, Wang, Zhiyao, Qiu, Yue, Wei, Min, Li, Chunyan, Xie, Yikuan, Shen, Le, Huang, Yuguang, Ma, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374701/
https://ncbi.nlm.nih.gov/pubmed/28359290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0822-9
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