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Monoamine oxidase B inhibitor, selegiline, reduces (18)F-THK5351 uptake in the human brain
BACKGROUND: (18)F-THK5351 is a quinoline-derived tau imaging agent with high affinity to paired helical filaments (PHF). However, high levels of (18)F-THK5351 retention in brain regions thought to contain negligible concentrations of PHF raise questions about the interpretation of the positron emiss...
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| Veröffentlicht in: | Alzheimers Res Ther |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374697/ https://ncbi.nlm.nih.gov/pubmed/28359327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0253-y |
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