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Curcumin suppresses gastric tumor cell growth via ROS-mediated DNA polymerase γ depletion disrupting cellular bioenergetics

BACKGROUND: Curcumin, as a pro-apoptotic agent, is extensively studied to inhibit tumor cell growth of various tumor types. Previous work has demonstrated that curcumin inhibits cancer cell growth by targeting multiple signaling transduction and cellular processes. However, the role of curcumin in r...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wang, Lihua, Chen, Xiwen, Du, Zhuanyun, Li, Gefei, Chen, Mayun, Chen, Xi, Liang, Guang, Chen, Tongke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374654/
https://ncbi.nlm.nih.gov/pubmed/28359291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0513-5
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