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Prion-like characteristics of the bacterial protein Microcin E492
Microcin E492 (Mcc) is a pore-forming bacteriotoxin. Mcc activity is inhibited at the stationary phase by formation of amyloid-like aggregates in the culture. Here we report that, in a similar manner as prions, Mcc naturally exists as two conformers: a β-sheet-rich, protease-resistant, aggregated, i...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374632/ https://ncbi.nlm.nih.gov/pubmed/28361921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45720 |
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