MYCN amplification predicts poor prognosis based on interphase fluorescence in situ hybridization analysis of bone marrow cells in bone marrow metastases of neuroblastoma

BACKGROUND: MYCN gene amplification is related to risk stratification. Therefore it is important to identify accurately the level of the MYCN gene as early as possible in neuroblastoma (NB); however, for patients with bone marrow (BM) metastasis who need chemotherapy before surgery, timely detection...

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Publicado en:Cancer Cell Int
Autores principales: Yue, Zhi-Xia, Huang, Cheng, Gao, Chao, Xing, Tian-Yu, Liu, Shu-Guang, Li, Xing-Jun, Zhao, Qian, Wang, Xi-Si, Zhao, Wen, Jin, Mei, Ma, Xiao-Li
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374581/
https://ncbi.nlm.nih.gov/pubmed/28367105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-017-0412-z
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