MYCN amplification plus 1p36 loss of heterozygosity predicts ultra high risk in bone marrow metastatic neuroblastoma

Abstract Background This study aimed to better understand the prognostic effect of multiple genetic markers and identify more subpopulations at ultra high risk of poor outcome in bone marrow (BM) metastatic neuroblastoma (NB). Methods We screened the MYCN, 1p36 and 11q23 loss of heterozygosity (LOH)...

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Detalhes bibliográficos
Main Authors: Zhi‐Xia Yue, Tian‐Yu Xing, Wen Zhao, Qian Zhao, Xi‐Si Wang, Yan Su, Chao Gao, Shu‐Guang Liu, Xiao‐Li Ma
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-04-01
Colecção:Cancer Medicine
Assuntos:
11q23 LOH
1p36 LOH
bone marrow metastasis
fluorescence in situ hybridization
MYCN amplification
neuroblastoma
Acesso em linha:https://doi.org/10.1002/cam4.4583
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