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Tumour blood vessel normalisation by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumour mouse model

Blood vessels are important tissue structures that deliver oxygen and nutrition. In tumour tissue, abnormal blood vessels, which are hyperpermeable and immature, are often formed; these tissues also have irregular vascularisation and intravasation. This situation leads to hypoperfusion in tumour tis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Koyama, Satoshi, Matsunaga, Shinji, Imanishi, Masaki, Maekawa, Yoichi, Kitano, Hiroya, Takeuchi, Hiromi, Tomita, Shuhei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374523/
https://ncbi.nlm.nih.gov/pubmed/28361934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45621
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