Enhanced store-operated Ca(2+) influx and ORAI1 expression in ventricular fibroblasts from human failing heart

Excessive cardiac fibrosis, characterized by increased collagen-rich extracellular matrix (ECM) deposition, is a major predisposing factor for mechanical and electrical dysfunction in heart failure (HF). The human ventricular fibroblast (hVF) remodeling mechanisms that cause excessive collagen depos...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Ross, Gracious R., Bajwa, Tanvir, Edwards, Stacie, Emelyanova, Larisa, Rizvi, Farhan, Holmuhamedov, Ekhson L., Werner, Paul, Downey, Francis X., Tajik, A. Jamil, Jahangir, Arshad
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374400/
https://ncbi.nlm.nih.gov/pubmed/28126709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.022632
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