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The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1

miR-1 is a small noncoding RNA molecule that modulates gene expression in heart and skeletal muscle. Loss of Drosophila miR-1 produces defects in somatic muscle and embryonic heart development, which have been partly attributed to miR-1 directly targeting Delta to decrease Notch signaling. Here, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Zhu, Jun-yi, Heidersbach, Amy, Kathiriya, Irfan S., Garay, Bayardo I., Ivey, Kathryn N., Srivastava, Deepak, Han, Zhe, King, Isabelle N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374346/
https://ncbi.nlm.nih.gov/pubmed/28246214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.140368
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