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Neuroblast niche position is controlled by Phosphoinositide 3-kinase-dependent DE-Cadherin adhesion

Correct positioning of stem cells within their niche is essential for tissue morphogenesis and homeostasis. How stem cells acquire and maintain niche position remains largely unknown. Here, we show that a subset of brain neuroblasts (NBs) in Drosophila utilize Phosphoinositide 3-kinase (PI3-kinase)...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Doyle, Susan E., Pahl, Matthew C., Siller, Karsten H., Ardiff, Lindsay, Siegrist, Sarah E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374343/
https://ncbi.nlm.nih.gov/pubmed/28126840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.136713
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