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Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat

We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identified Cd36 as the gene underlying the chromosome 4...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Coan, Philip M., Hummel, Oliver, Garcia Diaz, Ana, Barrier, Marjorie, Alfazema, Neza, Norsworthy, Penny J., Pravenec, Michal, Petretto, Enrico, Hübner, Norbert, Aitman, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374317/
https://ncbi.nlm.nih.gov/pubmed/28130354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.026716
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