Determinants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA era

Acute promyelocytic leukemia (APL) is commonly complicated by a complex coagulopathy. Uncertainty remains as to which markers of bleeding risk are independent predictors. Drawing from 5 large clinical trials that included all-trans retinoic acid (ATRA) as part of induction, we assessed known determi...

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Опубликовано в: :Blood
Главные авторы: Mantha, Simon, Goldman, Debra A., Devlin, Sean M., Lee, Ju-Whei, Zannino, Diana, Collins, Marnie, Douer, Dan, Iland, Harry J., Litzow, Mark R., Stein, Eytan M., Appelbaum, Frederick R., Larson, Richard A., Stone, Richard, Powell, Bayard L., Geyer, Susan, Laumann, Kristina, Rowe, Jacob M., Erba, Harry, Coutre, Steven, Othus, Megan, Park, Jae H., Wiernik, Peter H., Tallman, Martin S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2017
Предметы:
Clinical Trials and Observations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374291/
https://ncbi.nlm.nih.gov/pubmed/28082441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-747170
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