Telomere Length Recovery a Strong Predictor of Overall Survival In Acute Promyelocytic Leukemia

Telomeres are the capping ends of chromosomes that protect the loss of genetic material and prevent chromosomal instability. In human tissue-specific stem/progenitor cells, telomere length is maintained by the telomerase complex, which consists of a reverse transcriptase catalytic subunit (TERT) and...

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Veröffentlicht in:Acta Haematol
Hauptverfasser: Baljevic, Muhamed, Dumitriu, Bogdan, Lee, Ju-Whei, Paietta, Elisabeth M., Wiernik, Peter H., Racevskis, Janis, Chen, Christina, Stein, Eytan M., Gallagher, Robert E., Rowe, Jacob M., Appelbaum, Frederick R., Powell, Bayard L., Larson, Richard A., Coutré, Steven E., Lancet, Jeffrey, Litzow, Mark R., Luger, Selina M., Young, Neal S., Tallman, Martin S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198772/
https://ncbi.nlm.nih.gov/pubmed/27632567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448160
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