Telomere Length Recovery a Strong Predictor of Overall Survival In Acute Promyelocytic Leukemia

Telomeres are the capping ends of chromosomes that protect the loss of genetic material and prevent chromosomal instability. In human tissue-specific stem/progenitor cells, telomere length is maintained by the telomerase complex, which consists of a reverse transcriptase catalytic subunit (TERT) and...

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Pubblicato in:Acta Haematol
Autori principali: Baljevic, Muhamed, Dumitriu, Bogdan, Lee, Ju-Whei, Paietta, Elisabeth M., Wiernik, Peter H., Racevskis, Janis, Chen, Christina, Stein, Eytan M., Gallagher, Robert E., Rowe, Jacob M., Appelbaum, Frederick R., Powell, Bayard L., Larson, Richard A., Coutré, Steven E., Lancet, Jeffrey, Litzow, Mark R., Luger, Selina M., Young, Neal S., Tallman, Martin S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198772/
https://ncbi.nlm.nih.gov/pubmed/27632567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448160
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