Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proximal Tubular Cells

Two natural compounds alisol A 24-acetate (24A) and alisol B 23-acetate (23B) are abundant in Rhizoma alismatis. In the present study, we evaluated the induction of 24A and 23B on apoptosis and possible nephrotoxicity of human renal proximal tubular (HK-2) cells by activating autophagy and also expl...

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Pubblicato in:Front Pharmacol
Autori principali: Wang, Chunfei, Feng, Liang, Ma, Liang, Chen, Haifeng, Tan, Xiaobin, Hou, Xuefeng, Song, Jie, Cui, Li, Liu, Dan, Chen, Juan, Yang, Nan, Wang, Jing, Liu, Ying, Zhao, Bingjie, Wang, Gang, Zhou, Yuanli, Jia, Xiaobin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374204/
https://ncbi.nlm.nih.gov/pubmed/28408883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00172
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