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Computational analysis of the human sinus node action potential: model development and effects of mutations

KEY POINTS: We constructed a comprehensive mathematical model of the spontaneous electrical activity of a human sinoatrial node (SAN) pacemaker cell, starting from the recent Severi–DiFrancesco model of rabbit SAN cells. Our model is based on electrophysiological data from isolated human SAN pacemak...

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Detaylı Bibliyografya
Yayımlandı:J Physiol
Asıl Yazarlar: Fabbri, Alan, Fantini, Matteo, Wilders, Ronald, Severi, Stefano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374121/
https://ncbi.nlm.nih.gov/pubmed/28185290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273259
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