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An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation
The cellular basis of cardiac pacemaking is still debated. Reliable computational models of the sinoatrial node (SAN) action potential (AP) may help gain a deeper understanding of the phenomenon. Recently, novel models incorporating detailed Ca(2+)-handling dynamics have been proposed, but they fail...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477753/ https://ncbi.nlm.nih.gov/pubmed/22711956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.229435 |
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