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Molecular mechanisms of Slo2 K(+) channel closure

KEY POINTS: Intracellular Na(+)‐activated Slo2 potassium channels are in a closed state under normal physiological conditions, although their mechanisms of ion permeation gating are not well understood. A cryo‐electron microscopy structure of Slo2.2 suggests that the ion permeation pathway of these...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Giese, M. Hunter, Gardner, Alison, Hansen, Angela, Sanguinetti, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374106/
https://ncbi.nlm.nih.gov/pubmed/27682982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273225
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