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Identification of the Intracellular Na(+) Sensor in Slo2.1 Potassium Channels
Slo2 potassium channels have a very low open probability under normal physiological conditions, but are readily activated in response to an elevated [Na(+)](i) (e.g. during ischemia). An intracellular Na(+) coordination motif (DX(R/K)XXH) was previously identified in Kir3.2, Kir3.4, Kir5.1, and Slo2...
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Publicado no: | J Biol Chem |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505520/ https://ncbi.nlm.nih.gov/pubmed/25903137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.653089 |
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