Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus

Psychiatric patients treated with lithium (Li(+)) may develop nephrogenic diabetes insipidus (NDI). Although the etiology of Li(+)-induced NDI (Li-NDI) is poorly understood, it occurs partially due to reduced aquaporin-2 (AQP2) expression in the kidney collecting ducts. A mechanism postulated for th...

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Udgivet i:JCI Insight
Main Authors: Poulsen, Søren Brandt, Kristensen, Tina Bøgelund, Brooks, Heddwen L., Kohan, Donald E., Rieg, Timo, Fenton, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374078/
https://ncbi.nlm.nih.gov/pubmed/28405619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91042
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