Prolonged activation of IL-5–producing ILC2 causes pulmonary arterial hypertrophy

IL-33 is one of the critical cytokines that activates group 2 innate lymphoid cells (ILC2s) and mediates allergic reactions. Accumulating evidence suggests that IL-33 is also involved in the pathogenesis of several chronic inflammatory diseases. Previously, we generated an IL-5 reporter mouse and re...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ikutani, Masashi, Tsuneyama, Koichi, Kawaguchi, Makoto, Fukuoka, Junya, Kudo, Fujimi, Nakae, Susumu, Arita, Makoto, Nagai, Yoshinori, Takaki, Satoshi, Takatsu, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374073/
https://ncbi.nlm.nih.gov/pubmed/28405615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90721
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