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RIP140 in monocytes/macrophages regulates osteoclast differentiation and bone homeostasis

Osteolytic bone diseases, such as osteoporosis, are characterized by diminished bone quality and increased fracture risk. The therapeutic challenge remains to maintain bone homeostasis with a balance between osteoclast-mediated resorption and osteoblast-mediated formation. Osteoclasts are formed by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Lee, Bomi, Iwaniec, Urszula T., Turner, Russell T., Lin, Yi-Wei, Clarke, Bart L., Gingery, Anne, Wei, Li-Na
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374065/
https://ncbi.nlm.nih.gov/pubmed/28405613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90517
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