RIP140 in monocytes/macrophages regulates osteoclast differentiation and bone homeostasis

Osteolytic bone diseases, such as osteoporosis, are characterized by diminished bone quality and increased fracture risk. The therapeutic challenge remains to maintain bone homeostasis with a balance between osteoclast-mediated resorption and osteoblast-mediated formation. Osteoclasts are formed by...

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Опубликовано в: :JCI Insight
Главные авторы: Lee, Bomi, Iwaniec, Urszula T., Turner, Russell T., Lin, Yi-Wei, Clarke, Bart L., Gingery, Anne, Wei, Li-Na
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374065/
https://ncbi.nlm.nih.gov/pubmed/28405613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90517
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