A potent in vivo anti-tumor efficacy of novel recombinant type I interferon

PURPOSE: Anti-proliferative, antiviral, and immunomodulatory activities of endogenous type I interferons (IFN1) prompt the design of recombinant IFN1 for therapeutic purposes. However, most of designed interferons exhibited suboptimal therapeutic efficacies against solid tumors. Here we report evalu...

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Publicado en:Clin Cancer Res
Autores principales: Zhang, Kang-Jian, Yin, Xiao-Fei, Yang, Yuan-Qin, Li, Hui-Ling, Xu, Yan-Ni, Chen, Lie-Yang, Liu, Xi-Jun, Yuan, Su-Jing, Fang, Xian-Long, Xiao, Jing, Wu, Shuai, Xu, Hai-Neng, Chu, Liang, Katlinski, Kanstantsin V., Katlinskaya, Yuliya V., Guo, Rong-Bing, Wei, Guang-Wen, Wang, Da-Cheng, Liu, Xin-Yuan, Fuchs, Serge Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373932/
https://ncbi.nlm.nih.gov/pubmed/27683179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1386
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