Prostaglandin-mediated inhibition of serotonin signaling controls the affective component of inflammatory pain

Pain is fundamentally unpleasant and induces a negative affective state. The affective component of pain is mediated by circuits that are distinct from those mediating the sensory-discriminative component. Here, we have investigated the role of prostaglandins in the affective dimension of pain using...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Singh, Anand Kumar, Zajdel, Joanna, Mirrasekhian, Elahe, Almoosawi, Nader, Frisch, Isabell, Klawonn, Anna M., Jaarola, Maarit, Fritz, Michael, Engblom, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373882/
https://ncbi.nlm.nih.gov/pubmed/28287401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90678
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