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A high-resolution map of transcriptional repression

Turning genes on and off is essential for development and homeostasis, yet little is known about the sequence and causal role of chromatin state changes during the repression of active genes. This is surprising, as defective gene silencing underlies developmental abnormalities and disease. Here we d...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Liang, Ziwei, Brown, Karen E, Carroll, Thomas, Taylor, Benjamin, Vidal, Isabel Ferreirós, Hendrich, Brian, Rueda, David, Fisher, Amanda G, Merkenschlager, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373822/
https://ncbi.nlm.nih.gov/pubmed/28318487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22767
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