A high-resolution map of transcriptional repression

Turning genes on and off is essential for development and homeostasis, yet little is known about the sequence and causal role of chromatin state changes during the repression of active genes. This is surprising, as defective gene silencing underlies developmental abnormalities and disease. Here we d...

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Udgivet i:eLife
Main Authors: Liang, Ziwei, Brown, Karen E, Carroll, Thomas, Taylor, Benjamin, Vidal, Isabel Ferreirós, Hendrich, Brian, Rueda, David, Fisher, Amanda G, Merkenschlager, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Genes and Chromosomes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373822/
https://ncbi.nlm.nih.gov/pubmed/28318487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22767
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