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Novel “Add-On” Molecule Based on Evans Blue Confers Superior Pharmacokinetics and Transforms Drugs to Theranostic Agents

One of the major design considerations for a drug is its pharmacokinetics in the blood. A drug with a short half-life in the blood is less available at a target organ. Such a limitation dictates treatment with either high doses or more frequent doses, both of which may increase the likelihood of und...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Nucl Med
Prif Awduron: Chen, Haojun, Jacobson, Orit, Niu, Gang, Weiss, Ido D., Kiesewetter, Dale O., Liu, Yi, Ma, Ying, Wu, Hua, Chen, Xiaoyuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society of Nuclear Medicine 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373503/
https://ncbi.nlm.nih.gov/pubmed/27879373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.116.182097
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