Chemical Conjugation of Evans Blue Derivative: A Strategy to Develop Long-Acting Therapeutics through Albumin Binding

The efficacy of therapeutic drugs is highly dependent on their optimal in vivo pharmacokinetics. Albumin conjugation is considered to be one of the most effective means of protracting the short lifespan of peptides and proteins. In this study, we proposed a novel platform for developing long lasting...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Chen, Haojun, Wang, Guohao, Lang, Lixin, Jacobson, Orit, Kiesewetter, Dale O., Liu, Yi, Ma, Ying, Zhang, Xianzhong, Wu, Hua, Zhu, Lei, Niu, Gang, Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729772/
https://ncbi.nlm.nih.gov/pubmed/26877782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.14322
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