APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death

People of African ancestry carrying certain APOL1 mutant alleles are at elevated risk of developing renal diseases. However, the mechanisms underlying APOL1-associated renal diseases are unknown. Because the APOL1 gene is unique to humans and some primates, new animal models are needed to understand...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Fu, Yulong, Zhu, Jun-yi, Richman, Adam, Zhang, Yi, Xie, Xuefang, Das, Jharna R., Li, Jinliang, Ray, Patricio E., Han, Zhe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2017
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373456/
https://ncbi.nlm.nih.gov/pubmed/27864430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050550
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