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ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression

The transcription factor GATA3 is the master regulator that drives mammary luminal epithelial cell differentiation and maintains mammary gland homeostasis. Loss of GATA3 is associated with aggressive breast cancer development. We have identified ZNF503/ZEPPO2 zinc-finger elbow-related proline domain...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shahi, Payam, Wang, Chih-Yang, Lawson, Devon A., Slorach, Euan M., Lu, Angela, Yu, Ying, Lai, Ming-Derg, Gonzalez Velozo, Hugo, Werb, Zena
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373372/
https://ncbi.nlm.nih.gov/pubmed/28258171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701690114
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