ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression

The transcription factor GATA3 is the master regulator that drives mammary luminal epithelial cell differentiation and maintains mammary gland homeostasis. Loss of GATA3 is associated with aggressive breast cancer development. We have identified ZNF503/ZEPPO2 zinc-finger elbow-related proline domain...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Shahi, Payam, Wang, Chih-Yang, Lawson, Devon A., Slorach, Euan M., Lu, Angela, Yu, Ying, Lai, Ming-Derg, Gonzalez Velozo, Hugo, Werb, Zena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373372/
https://ncbi.nlm.nih.gov/pubmed/28258171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701690114
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