Overexpression of Human SOD1 Leads to Discrete Defects in the Cerebellar Architecture in the Mouse

The human superoxide dismutase 1 (SOD1) gene is responsible for neutralizing supercharged oxygen radicals within the cell. Mutation in SOD1 gene causes amyotrophic lateral sclerosis (ALS). Recent studies have shown involvement of the cerebellum in ALS, although the cerebellar contribution in SOD1 tr...

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發表在:Front Neuroanat
Main Authors: Afshar, Pegah, Ashtari, Niloufar, Jiao, Xiaodan, Rahimi-Balaei, Maryam, Zhang, Xiaosha, Yaganeh, Behzad, Del Bigio, Marc R., Kong, Jiming, Marzban, Hassan
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372795/
https://ncbi.nlm.nih.gov/pubmed/28424594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2017.00022
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