Overexpression of Human SOD1 Leads to Discrete Defects in the Cerebellar Architecture in the Mouse

The human superoxide dismutase 1 (SOD1) gene is responsible for neutralizing supercharged oxygen radicals within the cell. Mutation in SOD1 gene causes amyotrophic lateral sclerosis (ALS). Recent studies have shown involvement of the cerebellum in ALS, although the cerebellar contribution in SOD1 tr...

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Vydáno v:Front Neuroanat
Hlavní autoři: Afshar, Pegah, Ashtari, Niloufar, Jiao, Xiaodan, Rahimi-Balaei, Maryam, Zhang, Xiaosha, Yaganeh, Behzad, Del Bigio, Marc R., Kong, Jiming, Marzban, Hassan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372795/
https://ncbi.nlm.nih.gov/pubmed/28424594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2017.00022
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