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Loss of prostatic acid phosphatase and α-synuclein cause motor circuit degeneration without altering cerebellar patterning

Prostatic acid phosphatase (PAP), which is secreted by prostate, increases in some diseases such as prostate cancer. PAP is also present in the central nervous system. In this study we reveal that α-synuclein (Snca) gene is co-deleted/mutated in PAP null mouse. It is indicated that mice deficient in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rahimi-Balaei, Maryam, Buchok, Matthew, Vihko, Pirkko, Parkinson, Fiona E., Marzban, Hassan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738605/
https://ncbi.nlm.nih.gov/pubmed/31509576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222234
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