Hif-1α Overexpression Improves Transplanted Bone Mesenchymal Stem Cells Survival in Rat MCAO Stroke Model

Bone mesenchymal stem cells (BMSCs) death after transplantation is a serious obstacle impacting on the outcome of cell therapy for cerebral infarction. This study was aimed to investigate whether modification of BMSCs with hypoxia-inducible factor 1α (Hif-1α) could enhance the survival of the implan...

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Publicado en:Front Mol Neurosci
Autores principales: Lv, Bingke, Li, Feng, Han, Jianbang, Fang, Jie, Xu, Limin, Sun, Chengmei, Hua, Tian, Zhang, Zhongfei, Feng, Zhiming, Jiang, Xiaodan
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372780/
https://ncbi.nlm.nih.gov/pubmed/28424584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00080
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