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The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus

Significance: Metabolic syndrome is a frequent precursor of type 2 diabetes mellitus (T2D), a disease that currently affects ∼8% of the adult population worldwide. Pancreatic beta-cell dysfunction and loss are central to the disease process, although understanding of the underlying molecular mechani...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Gerber, Philipp A., Rutter, Guy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372767/
https://ncbi.nlm.nih.gov/pubmed/27225690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6755
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