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Dealing with an Unconventional Genetic Code in Mitochondria: The Biogenesis and Pathogenic Defects of the 5-Formylcytosine Modification in Mitochondrial tRNA(Met)
Human mitochondria contain their own genome, which uses an unconventional genetic code. In addition to the standard AUG methionine codon, the single mitochondrial tRNA Methionine (mt-tRNA(Met)) also recognises AUA during translation initiation and elongation. Post-transcriptional modifications of tR...
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| Publicado no: | Biomolecules |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5372736/ https://ncbi.nlm.nih.gov/pubmed/28257121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7010024 |
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