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Role of Pseudouridine Formation by Deg1 for Functionality of Two Glutamine Isoacceptor tRNAs

Loss of Deg1/Pus3 and concomitant elimination of pseudouridine in tRNA at positions 38 and 39 (ψ38/39) was shown to specifically impair the function of tRNA(Gln)(UUG) under conditions of temperature-induced down-regulation of wobble uridine thiolation in budding yeast and is linked to intellectual d...

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Publicat a:Biomolecules
Autors principals: Klassen, Roland, Schaffrath, Raffael
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372720/
https://ncbi.nlm.nih.gov/pubmed/28134782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7010008
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