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Nrf2 Regulates the Risk of a Diesel Exhaust Inhalation-Induced Immune Response during Bleomycin Lung Injury and Fibrosis in Mice

The present study investigated the effects of diesel exhaust (DE) on an experimental model of bleomycin (BLM)-induced lung injury and fibrosis in mice. BLM was intravenously administered to both Nrf2(+/+) and Nrf2(−/−) C57BL/6J mice on day 0. The mice were exposed to DE for 56 days from 28 days befo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Li, Ying-Ji, Shimizu, Takako, Shinkai, Yusuke, Hirata, Yukiyo, Inagaki, Hirofumi, Takeda, Ken, Azuma, Arata, Yamamoto, Masayuki, Kawada, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372661/
https://ncbi.nlm.nih.gov/pubmed/28304344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030649
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